pueraria mirifica powder

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Miroestrol and Deoxymiroestrol are compounds exclusive to Pueraria Mirifica. They are more active than soy Isoflavones. As stated in the Journal of Natural Products, Deoxymiroestrol is readily oxidized to Miroestrol. So, it has been isolated and identified by German chemists in 1940 as the real chemical element of PM. The chemical composition of Miroestrol and Deoxymiroestrol resemble that of estradiol. Pueraria Mirifica has four soy Isoflavones: Genistein, Daidzein, Daidzin, and Genistin. Coumestrol and Mirificoumestan are in the Coumestan group of Phytoestrogens.
Pueraria Mirifica’s effects are similar to those of estrogen. Therefore, patients with asthma, diabetes, epilepsy, migraine, and lupus must be careful when using Pueraria Mirifica. Furthermore, individuals with abnormal triglycerides and hypercalcemia should take precautions. The herb could be toxic for individuals taking anticoagulants, thyroid medication, diabetes medication, birth control pills, or tamoxifen. Other Phytoestrogenic natural herbs should not be mixed with Pueraria Mirifica.
Calcium and magnesium are the two main metals in Pueraria Mirifica. The metals lower than 1 ppm are arsenic, cadmium, and mercury. Levels of copper and iron are 3.14 ppm and 258 ppm respectively. For Miroestrol and Puerarin, the respective levels are 795.00 mg and 446.00 mg. The Daidzin content is 164.00 mg/100gm, while Daidzein is 28.00 mg and Genistin is 52.00 mg.
An experiment about the effect of Pueraria Mirifica on serum PTH and calcium levels was done on monkeys. The monkeys were given three doses of PM: 10, 100, and 1,000 mg/day. PTH levels were low for two weeks after Pueraria Mirifica treatment. Serum PTH and calcium levels were steady when a monkey was a given a dose of 100 mg/day. Serum PTH and calcium levels declined in monkeys when they were treated with 1,000 mg/day PM dose. This means that Pueraria Mirifica is a remedy for bone loss induced by estrogen insufficiency.
A study found that Pueraria Mirifica could cause teat and vagina development in female pigs. Moreover, PM’s other effects were hair shedding and regrowth. The ovarian weights of female pigs treated with Pueraria Mirifica were lower than the one of the untested group. The pig’s body weight gained was not affected by Pueraria Mirifica. After PM treatment ended, teat length remained long and undeveloped. The pig’s vagina was still large. Vaginal mucus and flaked skin epidermis stopped. Ovarian development is hindered by Pueraria Mirifica, but oviductal, uterine and mammary gland development are caused by PM.

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